BDBM50384736 CHEMBL2037225
SMILES: Cc1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1
InChI Key: InChIKey=KSUYDMYYPQIEMM-QRVIBDJDSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50384736 (CHEMBL2037225) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of TRKA by HTRF assay | ACS Med Chem Lett 3: 140-145 (2012) Article DOI: 10.1021/ml200261d BindingDB Entry DOI: 10.7270/Q2SJ1MNM | |||||||||||
More data for this Ligand-Target Pair |