BDBM50384740 CHEMBL2037231

SMILES: Fc1ccc(Cn2c(=O)sn(-c3cccc(c3)C(F)(F)F)c2=O)cc1

InChI Key: InChIKey=LALWIWMPVDDDKI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Regulator of G-protein signaling 4 (RGS4) (Homo sapiens (Human))	BDBM50384740 (CHEMBL2037231) Show SMILES Fc1ccc(Cn2c(=O)sn(-c3cccc(c3)C(F)(F)F)c2=O)cc1 Show InChI InChI=1S/C16H10F4N2O2S/c17-12-6-4-10(5-7-12)9-21-14(23)22(25-15(21)24)13-3-1-2-11(8-13)16(18,19)20/h1-8H,9H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM50384740 (CHEMBL2037231) Show SMILES Fc1ccc(Cn2c(=O)sn(-c3cccc(c3)C(F)(F)F)c2=O)cc1 Show InChI InChI=1S/C16H10F4N2O2S/c17-12-6-4-10(5-7-12)9-21-14(23)22(25-15(21)24)13-3-1-2-11(8-13)16(18,19)20/h1-8H,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair