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BDBM50384742 CHEMBL2037233

SMILES: Fc1ccc(Cn2c(=O)sn(-c3cccc(Cl)c3)c2=O)cc1

InChI Key: InChIKey=XWJFVSPYHJYTNK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384742   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Regulator of G-protein signaling 4 (RGS4)


(Homo sapiens (Human))
BDBM50384742
PNG
(CHEMBL2037233)
Show SMILES Fc1ccc(Cn2c(=O)sn(-c3cccc(Cl)c3)c2=O)cc1
Show InChI InChI=1S/C15H10ClFN2O2S/c16-11-2-1-3-13(8-11)19-14(20)18(15(21)22-19)9-10-4-6-12(17)7-5-10/h1-8H,9H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 52n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assay


ACS Med Chem Lett 3: 146-150 (2012)


Article DOI: 10.1021/ml200263y
More data for this
Ligand-Target Pair
Regulator of G-protein signaling 8


(Homo sapiens (Human))
BDBM50384742
PNG
(CHEMBL2037233)
Show SMILES Fc1ccc(Cn2c(=O)sn(-c3cccc(Cl)c3)c2=O)cc1
Show InChI InChI=1S/C15H10ClFN2O2S/c16-11-2-1-3-13(8-11)19-14(20)18(15(21)22-19)9-10-4-6-12(17)7-5-10/h1-8H,9H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 1.28E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assay


ACS Med Chem Lett 3: 146-150 (2012)


Article DOI: 10.1021/ml200263y
More data for this
Ligand-Target Pair