BDBM50384772 CHEMBL2037370

SMILES: Cc1ccc(Cn2c(O)cn(-c3ccc(C)cc3)c2=O)cc1

InChI Key: InChIKey=FEMNDRBAWKPHMB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM50384772 (CHEMBL2037370) Show SMILES Cc1ccc(Cn2c(O)cn(-c3ccc(C)cc3)c2=O)cc1 Show InChI InChI=1S/C18H18N2O2/c1-13-3-7-15(8-4-13)11-20-17(21)12-19(18(20)22)16-9-5-14(2)6-10-16/h3-10,12,21H,11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 4 (RGS4) (Homo sapiens (Human))	BDBM50384772 (CHEMBL2037370) Show SMILES Cc1ccc(Cn2c(O)cn(-c3ccc(C)cc3)c2=O)cc1 Show InChI InChI=1S/C18H18N2O2/c1-13-3-7-15(8-4-13)11-20-17(21)12-19(18(20)22)16-9-5-14(2)6-10-16/h3-10,12,21H,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair