BDBM50384773 CHEMBL2037371

SMILES: Cc1ccc(cc1)C1=CC(=O)N(Cc2ccccc2)C1=O

InChI Key: InChIKey=PLQCDKKQKRJJDK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50384773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Regulator of G-protein signaling 4 (RGS4) (Homo sapiens (Human))	BDBM50384773 (CHEMBL2037371) Show SMILES Cc1ccc(cc1)C1=CC(=O)N(Cc2ccccc2)C1=O |t:8| Show InChI InChI=1S/C18H15NO2/c1-13-7-9-15(10-8-13)16-11-17(20)19(18(16)21)12-14-5-3-2-4-6-14/h2-11H,12H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; The University of Bath US Patent					Assay Description FCPIA Characterization of RGS Inhibitory Activity: CCG-50014 (FIG. 1) was originally identified as a potential inhibitor of RGS8 and RGS16 in a polyp...				US Patent US8865750 (2014) BindingDB Entry DOI: 10.7270/Q20000TC
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 4 (RGS4) (Homo sapiens (Human))	BDBM50384773 (CHEMBL2037371) Show SMILES Cc1ccc(cc1)C1=CC(=O)N(Cc2ccccc2)C1=O |t:8| Show InChI InChI=1S/C18H15NO2/c1-13-7-9-15(10-8-13)16-11-17(20)19(18(16)21)12-14-5-3-2-4-6-14/h2-11H,12H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM50384773 (CHEMBL2037371) Show SMILES Cc1ccc(cc1)C1=CC(=O)N(Cc2ccccc2)C1=O |t:8| Show InChI InChI=1S/C18H15NO2/c1-13-7-9-15(10-8-13)16-11-17(20)19(18(16)21)12-14-5-3-2-4-6-14/h2-11H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; The University of Bath US Patent					Assay Description FCPIA Characterization of RGS Inhibitory Activity: CCG-50014 (FIG. 1) was originally identified as a potential inhibitor of RGS8 and RGS16 in a polyp...				US Patent US8865750 (2014) BindingDB Entry DOI: 10.7270/Q20000TC
					More data for this Ligand-Target Pair