BDBM50384774 CHEMBL1917204

SMILES: Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O

InChI Key: InChIKey=QUIIIYITNGOFEI-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50384774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Regulator of G-protein signaling 4 (RGS4) (Homo sapiens (Human))	BDBM50384774 (CHEMBL1917204) Show SMILES Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O Show InChI InChI=1S/C16H13FN2O2S/c1-11-2-8-14(9-3-11)19-15(20)18(16(21)22-19)10-12-4-6-13(17)7-5-12/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; The University of Bath US Patent					Assay Description FCPIA Characterization of RGS Inhibitory Activity: CCG-50014 (FIG. 1) was originally identified as a potential inhibitor of RGS8 and RGS16 in a polyp...				US Patent US8865750 (2014) BindingDB Entry DOI: 10.7270/Q20000TC
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM50384774 (CHEMBL1917204) Show SMILES Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O Show InChI InChI=1S/C16H13FN2O2S/c1-11-2-8-14(9-3-11)19-15(20)18(16(21)22-19)10-12-4-6-13(17)7-5-12/h2-9H,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; The University of Bath US Patent					Assay Description FCPIA Characterization of RGS Inhibitory Activity: CCG-50014 (FIG. 1) was originally identified as a potential inhibitor of RGS8 and RGS16 in a polyp...				US Patent US8865750 (2014) BindingDB Entry DOI: 10.7270/Q20000TC
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 4 (RGS4) (Homo sapiens (Human))	BDBM50384774 (CHEMBL1917204) Show SMILES Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O Show InChI InChI=1S/C16H13FN2O2S/c1-11-2-8-14(9-3-11)19-15(20)18(16(21)22-19)10-12-4-6-13(17)7-5-12/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM50384774 (CHEMBL1917204) Show SMILES Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O Show InChI InChI=1S/C16H13FN2O2S/c1-11-2-8-14(9-3-11)19-15(20)18(16(21)22-19)10-12-4-6-13(17)7-5-12/h2-9H,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; The University of Bath US Patent					Assay Description FCPIA Characterization of RGS Inhibitory Activity: CCG-50014 (FIG. 1) was originally identified as a potential inhibitor of RGS8 and RGS16 in a polyp...				US Patent US8865750 (2014) BindingDB Entry DOI: 10.7270/Q20000TC
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM50384774 (CHEMBL1917204) Show SMILES Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O Show InChI InChI=1S/C16H13FN2O2S/c1-11-2-8-14(9-3-11)19-15(20)18(16(21)22-19)10-12-4-6-13(17)7-5-12/h2-9H,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assay				ACS Med Chem Lett 3: 146-150 (2012) Article DOI: 10.1021/ml200263y BindingDB Entry DOI: 10.7270/Q2NS0VXW
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM50384774 (CHEMBL1917204) Show SMILES Cc1ccc(cc1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O Show InChI InChI=1S/C16H13FN2O2S/c1-11-2-8-14(9-3-11)19-15(20)18(16(21)22-19)10-12-4-6-13(17)7-5-12/h2-9H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; The University of Bath US Patent					Assay Description FCPIA Characterization of RGS Inhibitory Activity: CCG-50014 (FIG. 1) was originally identified as a potential inhibitor of RGS8 and RGS16 in a polyp...				US Patent US8865750 (2014) BindingDB Entry DOI: 10.7270/Q20000TC
					More data for this Ligand-Target Pair