BDBM50385107 CHEMBL2035877

SMILES: CC(C)c1cc(Oc2c(C)cc(NC(=O)CC(O)=O)c(C)c2C)ccc1O

InChI Key: InChIKey=RKNMDWYQIVLKAB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50385107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50385107 (CHEMBL2035877) Show SMILES CC(C)c1cc(Oc2c(C)cc(NC(=O)CC(O)=O)c(C)c2C)ccc1O Show InChI InChI=1S/C21H25NO5/c1-11(2)16-9-15(6-7-18(16)23)27-21-12(3)8-17(13(4)14(21)5)22-19(24)10-20(25)26/h6-9,11,23H,10H2,1-5H3,(H,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	20.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]T3 from human recombinant thyroid harmone receptor beta after 16 to 48 hrs by gamma-ray detection				Bioorg Med Chem 20: 3622-34 (2012) Article DOI: 10.1016/j.bmc.2012.03.056 BindingDB Entry DOI: 10.7270/Q2SF2X6V
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50385107 (CHEMBL2035877) Show SMILES CC(C)c1cc(Oc2c(C)cc(NC(=O)CC(O)=O)c(C)c2C)ccc1O Show InChI InChI=1S/C21H25NO5/c1-11(2)16-9-15(6-7-18(16)23)27-21-12(3)8-17(13(4)14(21)5)22-19(24)10-20(25)26/h6-9,11,23H,10H2,1-5H3,(H,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]T3 from human recombinant thyroid harmone receptor alpha after 16 to 48 hrs by gamma-ray detection				Bioorg Med Chem 20: 3622-34 (2012) Article DOI: 10.1016/j.bmc.2012.03.056 BindingDB Entry DOI: 10.7270/Q2SF2X6V
					More data for this Ligand-Target Pair