BDBM50385286 CHEMBL2035477

SMILES: Fc1ccc2[se]n(CCCCn3[se]c4ccc(F)cc4c3=O)c(=O)c2c1

InChI Key: InChIKey=FXBHJKRZVKFXAZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thioredoxin reductase 1, cytoplasmic (Rattus norvegicus)	BDBM50385286 (CHEMBL2035477) Show SMILES Fc1ccc2[se]n(CCCCn3[se]c4ccc(F)cc4c3=O)c(=O)c2c1 Show InChI InChI=1S/C18H14F2N2O2Se2/c19-11-3-5-15-13(9-11)17(23)21(25-15)7-1-2-8-22-18(24)14-10-12(20)4-6-16(14)26-22/h3-6,9-10H,1-2,7-8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay				Bioorg Med Chem 20: 3816-27 (2012) Article DOI: 10.1016/j.bmc.2012.04.033 BindingDB Entry DOI: 10.7270/Q2V69KND
					More data for this Ligand-Target Pair