BDBM50385305 CHEMBL2035472

SMILES: Cc1ccc2[se]n(CCCCn3[se]c4ccc(C)cc4c3=O)c(=O)c2c1

InChI Key: InChIKey=AUCQEWGOMMZSQY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thioredoxin reductase 1, cytoplasmic (Rattus norvegicus)	BDBM50385305 (CHEMBL2035472) Show SMILES Cc1ccc2[se]n(CCCCn3[se]c4ccc(C)cc4c3=O)c(=O)c2c1 Show InChI InChI=1S/C20H20N2O2Se2/c1-13-5-7-17-15(11-13)19(23)21(25-17)9-3-4-10-22-20(24)16-12-14(2)6-8-18(16)26-22/h5-8,11-12H,3-4,9-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay				Bioorg Med Chem 20: 3816-27 (2012) Article DOI: 10.1016/j.bmc.2012.04.033 BindingDB Entry DOI: 10.7270/Q2V69KND
					More data for this Ligand-Target Pair