BDBM50385405 CHEMBL2036576

SMILES: CN1CCN(CC1)c1ccc(NC(=O)c2nnc(Nc3ccccc3F)o2)cn1

InChI Key: InChIKey=DLBKGVUOCQAPRH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50385405 (CHEMBL2036576) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2nnc(Nc3ccccc3F)o2)cn1 Show InChI InChI=1S/C19H20FN7O2/c1-26-8-10-27(11-9-26)16-7-6-13(12-21-16)22-17(28)18-24-25-19(29-18)23-15-5-3-2-4-14(15)20/h2-7,12H,8-11H2,1H3,(H,22,28)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...				Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4
					More data for this Ligand-Target Pair