BDBM50385406 CHEMBL2036577

SMILES: CC(=O)N1CCN(CC1)c1ccc(NC(=O)c2nnc(Nc3ccccc3F)o2)cc1

InChI Key: InChIKey=KTHOPPXEAJKDJZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50385406 (CHEMBL2036577) Show SMILES CC(=O)N1CCN(CC1)c1ccc(NC(=O)c2nnc(Nc3ccccc3F)o2)cc1 Show InChI InChI=1S/C21H21FN6O3/c1-14(29)27-10-12-28(13-11-27)16-8-6-15(7-9-16)23-19(30)20-25-26-21(31-20)24-18-5-3-2-4-17(18)22/h2-9H,10-13H2,1H3,(H,23,30)(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...				Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4
					More data for this Ligand-Target Pair