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BDBM50385414 CHEMBL2036585

SMILES: Fc1ccccc1Nc1nnc(o1)C(=O)Nc1ccc(Nc2ccccc2)nc1

InChI Key: InChIKey=VNQMVRNFJVTDAJ-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385414   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 1 (DGAT1)


(Homo sapiens (Human))
BDBM50385414
PNG
(CHEMBL2036585)
Show SMILES Fc1ccccc1Nc1nnc(o1)C(=O)Nc1ccc(Nc2ccccc2)nc1
Show InChI InChI=1S/C20H15FN6O2/c21-15-8-4-5-9-16(15)25-20-27-26-19(29-20)18(28)24-14-10-11-17(22-12-14)23-13-6-2-1-3-7-13/h1-12H,(H,22,23)(H,24,28)(H,25,27)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...


Bioorg Med Chem Lett 22: 3873-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.117
BindingDB Entry DOI: 10.7270/Q2T72JG4
More data for this
Ligand-Target Pair