BDBM50385432 CHEMBL2036737

SMILES: CC(C)(C(=O)Nc1nnc(o1)C(=O)Nc1ccc(cc1)N1CCOCC1)c1ccc(Cl)cc1

InChI Key: InChIKey=PQAPOLUOGYUHFT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50385432 (CHEMBL2036737) Show SMILES CC(C)(C(=O)Nc1nnc(o1)C(=O)Nc1ccc(cc1)N1CCOCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H24ClN5O4/c1-23(2,15-3-5-16(24)6-4-15)21(31)26-22-28-27-20(33-22)19(30)25-17-7-9-18(10-8-17)29-11-13-32-14-12-29/h3-10H,11-14H2,1-2H3,(H,25,30)(H,26,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...				Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4
					More data for this Ligand-Target Pair