BDBM50385433 CHEMBL2036738

SMILES: Clc1ccc(cc1)C1(CCC1)C(=O)Nc1nnc(o1)C(=O)Nc1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=SGNDVLKBECZULH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50385433 (CHEMBL2036738) Show SMILES Clc1ccc(cc1)C1(CCC1)C(=O)Nc1nnc(o1)C(=O)Nc1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C24H24ClN5O4/c25-17-4-2-16(3-5-17)24(10-1-11-24)22(32)27-23-29-28-21(34-23)20(31)26-18-6-8-19(9-7-18)30-12-14-33-15-13-30/h2-9H,1,10-15H2,(H,26,31)(H,27,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...				Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4
					More data for this Ligand-Target Pair