BDBM50385434 CHEMBL2036739

SMILES: Clc1ccc(cc1)C1(CCCC1)C(=O)Nc1nnc(o1)C(=O)Nc1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=XHQCVTXKMOCNKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50385434 (CHEMBL2036739) Show SMILES Clc1ccc(cc1)C1(CCCC1)C(=O)Nc1nnc(o1)C(=O)Nc1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C25H26ClN5O4/c26-18-5-3-17(4-6-18)25(11-1-2-12-25)23(33)28-24-30-29-22(35-24)21(32)27-19-7-9-20(10-8-19)31-13-15-34-16-14-31/h3-10H,1-2,11-16H2,(H,27,32)(H,28,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...				Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4
					More data for this Ligand-Target Pair