BDBM50385647 CHEMBL2041956

SMILES: Fc1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccncc1

InChI Key: InChIKey=BFFCICPAPKEAMR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50385647 (CHEMBL2041956) Show SMILES Fc1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccncc1 Show InChI InChI=1S/C20H12FNO2/c21-15-7-5-13(6-8-15)18-19(23)16-3-1-2-4-17(16)24-20(18)14-9-11-22-12-10-14/h1-12H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	813	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK after 40 mins by scintillation counting				J Med Chem 54: 7427-31 (2011) Article DOI: 10.1021/jm200818j BindingDB Entry DOI: 10.7270/Q2R78G7T
					More data for this Ligand-Target Pair