BDBM50385649 CHEMBL2041958

SMILES: CC(C)Nc1cc(ccn1)-c1oc2ccccc2c(=O)c1-c1ccc(F)cc1

InChI Key: InChIKey=YOPQQIOJKPUFON-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50385649 (CHEMBL2041958) Show SMILES CC(C)Nc1cc(ccn1)-c1oc2ccccc2c(=O)c1-c1ccc(F)cc1 Show InChI InChI=1S/C23H19FN2O2/c1-14(2)26-20-13-16(11-12-25-20)23-21(15-7-9-17(24)10-8-15)22(27)18-5-3-4-6-19(18)28-23/h3-14H,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK after 40 mins by scintillation counting				J Med Chem 54: 7427-31 (2011) Article DOI: 10.1021/jm200818j BindingDB Entry DOI: 10.7270/Q2R78G7T
					More data for this Ligand-Target Pair