BDBM50385650 CHEMBL2041959

SMILES: CCCCNc1cc(ccn1)-c1oc2ccccc2c(=O)c1-c1ccc(F)cc1

InChI Key: InChIKey=GCLFSTRHXBWWSX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50385650 (CHEMBL2041959) Show SMILES CCCCNc1cc(ccn1)-c1oc2ccccc2c(=O)c1-c1ccc(F)cc1 Show InChI InChI=1S/C24H21FN2O2/c1-2-3-13-26-21-15-17(12-14-27-21)24-22(16-8-10-18(25)11-9-16)23(28)19-6-4-5-7-20(19)29-24/h4-12,14-15H,2-3,13H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK after 40 mins by scintillation counting				J Med Chem 54: 7427-31 (2011) Article DOI: 10.1021/jm200818j BindingDB Entry DOI: 10.7270/Q2R78G7T
					More data for this Ligand-Target Pair