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SMILES: Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ncccc21)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=CPBRQQKLCJBJCH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385856   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))		BDBM50385856
PNG
(CHEMBL2042995)
Show SMILES Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ncccc21)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C30H28N4O/c1-22-7-5-17-31-27(22)21-33-19-15-30(16-20-33)26-10-6-18-32-28(26)34(29(30)35)25-13-11-24(12-14-25)23-8-3-2-4-9-23/h2-14,17-18H,15-16,19-21H2,1H3
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MMDB

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PC cid
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n/an/a 1.60n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...

J Med Chem 55: 2945-59 (2012)


Article DOI: 10.1021/jm201542d
BindingDB Entry DOI: 10.7270/Q27945QW
More data for this
Ligand-Target Pair