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SMILES: CC(C)[C@H](NC(=O)c1cc(no1)-c1ccc(NC(=O)Nc2ccc(C)c(F)c2)cc1)C(O)=O

InChI Key: InChIKey=AFMVRKIHMDIRLX-FQEVSTJZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386146   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chondroitin sulfate N-acetylgalactosaminyltransferase 1


(Homo sapiens (Human))		BDBM50386146
PNG
(CHEMBL2042348)
Show SMILES CC(C)[C@H](NC(=O)c1cc(no1)-c1ccc(NC(=O)Nc2ccc(C)c(F)c2)cc1)C(O)=O |r|
Show InChI InChI=1S/C23H23FN4O5/c1-12(2)20(22(30)31)27-21(29)19-11-18(28-33-19)14-5-8-15(9-6-14)25-23(32)26-16-7-4-13(3)17(24)10-16/h4-12,20H,1-3H3,(H,27,29)(H,30,31)(H2,25,26,32)/t20-/m0/s1
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Article
PubMed
n/an/a 1.78E+5n/an/an/an/an/an/a



Piramal Healthcare Limited

Curated by ChEMBL


Assay Description
Inhibition of human DGAT1 assessed as conversion of [14C]-oleoyl-CoA to [14C]-triglyceride after 10 mins by scintillation counting

Eur J Med Chem 54: 324-42 (2012)


Article DOI: 10.1016/j.ejmech.2012.05.016
BindingDB Entry DOI: 10.7270/Q25B03HK
More data for this
Ligand-Target Pair