BDBM50386199 CHEMBL2042814

SMILES: CCc1cc(F)c2ccccc2c1CNC(=O)c1c2OC3=CC(=O)C(C(C)=O)C(=O)[C@@]3(C)c2c(O)cc1OC

InChI Key: InChIKey=UZSWJCGMMXLNGV-BXFARTRRSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50386199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50386199 (CHEMBL2042814) Show SMILES CCc1cc(F)c2ccccc2c1CNC(=O)c1c2OC3=CC(=O)C(C(C)=O)C(=O)[C@@]3(C)c2c(O)cc1OC |r,t:22| Show InChI InChI=1S/C30H26FNO7/c1-5-15-10-19(31)17-9-7-6-8-16(17)18(15)13-32-29(37)25-22(38-4)11-21(35)26-27(25)39-23-12-20(34)24(14(2)33)28(36)30(23,26)3/h6-12,24,35H,5,13H2,1-4H3,(H,32,37)/t24?,30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Modulation of human GAL4-fused PPARgamma LBD expressed in COS7 cells co-expressing pG5luc by luciferase reporter gene based transactivation assay				Eur J Med Chem 54: 522-33 (2012) Article DOI: 10.1016/j.ejmech.2012.05.040 BindingDB Entry DOI: 10.7270/Q2CV4JS3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50386199 (CHEMBL2042814) Show SMILES CCc1cc(F)c2ccccc2c1CNC(=O)c1c2OC3=CC(=O)C(C(C)=O)C(=O)[C@@]3(C)c2c(O)cc1OC |r,t:22| Show InChI InChI=1S/C30H26FNO7/c1-5-15-10-19(31)17-9-7-6-8-16(17)18(15)13-32-29(37)25-22(38-4)11-21(35)26-27(25)39-23-12-20(34)24(14(2)33)28(36)30(23,26)3/h6-12,24,35H,5,13H2,1-4H3,(H,32,37)/t24?,30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.940	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Modulation of full-length human pSG5-fused PPARgamma expressed in MG-63 cells co-expressing pGV-P2-PPRE after 24 hrs by luciferase reporter gene base...				Eur J Med Chem 54: 522-33 (2012) Article DOI: 10.1016/j.ejmech.2012.05.040 BindingDB Entry DOI: 10.7270/Q2CV4JS3
					More data for this Ligand-Target Pair