BDBM50386300 CHEMBL2047853
SMILES: CON1C(=O)[C@@H](N)Cc2ccccc12
InChI Key: InChIKey=UYXSPCLQWKBUEW-QMMMGPOBSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (Homo sapiens (Human)) | BDBM50386300 (CHEMBL2047853) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs | ACS Med Chem Lett 3: 187-192 (2012) Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynurenine/alpha-aminoadipate aminotransferase (Rattus norvegicus) | BDBM50386300 (CHEMBL2047853) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs | ACS Med Chem Lett 3: 187-192 (2012) Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135 | |||||||||||
More data for this Ligand-Target Pair |