BDBM50386304 CHEMBL2047857

SMILES: COc1cccc2C[C@H](N)C(=O)N(O)c12

InChI Key: InChIKey=NPUNCEBASKWUPN-ZETCQYMHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50386304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (Homo sapiens (Human))	BDBM50386304 (CHEMBL2047857) Show SMILES COc1cccc2C[C@H](N)C(=O)N(O)c12 |r| Show InChI InChI=1S/C10H12N2O3/c1-15-8-4-2-3-6-5-7(11)10(13)12(14)9(6)8/h2-4,7,14H,5,11H2,1H3/t7-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	572	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs				ACS Med Chem Lett 3: 187-192 (2012) Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135
					More data for this Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase (Rattus norvegicus)	BDBM50386304 (CHEMBL2047857) Show SMILES COc1cccc2C[C@H](N)C(=O)N(O)c12 |r| Show InChI InChI=1S/C10H12N2O3/c1-15-8-4-2-3-6-5-7(11)10(13)12(14)9(6)8/h2-4,7,14H,5,11H2,1H3/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs				ACS Med Chem Lett 3: 187-192 (2012) Article DOI: 10.1021/ml200204m BindingDB Entry DOI: 10.7270/Q2MC9135
					More data for this Ligand-Target Pair