BDBM50386409 CHEMBL2047299

SMILES: CC(C)CC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1

InChI Key: InChIKey=MOFSYUGAGGTVIT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50386409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50386409 (CHEMBL2047299) Show SMILES CC(C)CC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1 Show InChI InChI=1S/C18H19BrN2O2/c1-12(2)10-17(22)20-13-6-5-7-14(11-13)21-18(23)15-8-3-4-9-16(15)19/h3-9,11-12H,10H2,1-2H3,(H,20,22)(H,21,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Marquette University Curated by ChEMBL					Assay Description Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...				Bioorg Med Chem 26: 2514-2529 (2018) Article DOI: 10.1016/j.bmc.2018.04.016 BindingDB Entry DOI: 10.7270/Q23R0WHM
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50386409 (CHEMBL2047299) Show SMILES CC(C)CC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1 Show InChI InChI=1S/C18H19BrN2O2/c1-12(2)10-17(22)20-13-6-5-7-14(11-13)21-18(23)15-8-3-4-9-16(15)19/h3-9,11-12H,10H2,1-2H3,(H,20,22)(H,21,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of SFLLRN-NH2-stimulated PAR1-mediated platelet activation in platelet-rich human plasma assessed as surface expression of P-selectin afte...				ACS Med Chem Lett 3: 232-237 (2012) Article DOI: 10.1021/ml2002696 BindingDB Entry DOI: 10.7270/Q2Q52QP8
					More data for this Ligand-Target Pair