null

SMILES: COc1ccc(CC(=NN)C(=O)NCCSSCCNC(=O)C(Cc2ccc(OC)c(Br)c2)=NN)cc1Br

InChI Key: InChIKey=FKSNJACQQDIITN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50386471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50386471 (CHEMBL2047679) Show SMILES COc1ccc(CC(=NN)C(=O)NCCSSCCNC(=O)C(Cc2ccc(OC)c(Br)c2)=NN)cc1Br |w:8.8,33.34| Show InChI InChI=1S/C24H30Br2N6O4S2/c1-35-21-5-3-15(11-17(21)25)13-19(31-27)23(33)29-7-9-37-38-10-8-30-24(34)20(32-28)14-16-4-6-22(36-2)18(26)12-16/h3-6,11-12H,7-10,13-14,27-28H2,1-2H3,(H,29,33)(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...				J Med Chem 55: 1731-50 (2012) Article DOI: 10.1021/jm2016182 BindingDB Entry DOI: 10.7270/Q22F7PHC
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50386471 (CHEMBL2047679) Show SMILES COc1ccc(CC(=NN)C(=O)NCCSSCCNC(=O)C(Cc2ccc(OC)c(Br)c2)=NN)cc1Br |w:8.8,33.34| Show InChI InChI=1S/C24H30Br2N6O4S2/c1-35-21-5-3-15(11-17(21)25)13-19(31-27)23(33)29-7-9-37-38-10-8-30-24(34)20(32-28)14-16-4-6-22(36-2)18(26)12-16/h3-6,11-12H,7-10,13-14,27-28H2,1-2H3,(H,29,33)(H,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescen...				J Med Chem 55: 1731-50 (2012) Article DOI: 10.1021/jm2016182 BindingDB Entry DOI: 10.7270/Q22F7PHC
					More data for this Ligand-Target Pair