BDBM50386550 CHEMBL2048236

SMILES: OP(O)(=O)C(F)(Cc1cncc(c1)-c1ccccc1)P(O)(O)=O

InChI Key: InChIKey=LFOWDGCSYVDQLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50386550 (CHEMBL2048236) Show SMILES OP(O)(=O)C(F)(Cc1cncc(c1)-c1ccccc1)P(O)(O)=O Show InChI InChI=1S/C13H14FNO6P2/c14-13(22(16,17)18,23(19,20)21)7-10-6-12(9-15-8-10)11-4-2-1-3-5-11/h1-6,8-9H,7H2,(H2,16,17,18)(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal-His6 tagged FPPS expressed in Escherichia coli BL21 using [14C]IPP and GPP as substrate incubated for 10 m...				J Med Chem 55: 3201-15 (2012) Article DOI: 10.1021/jm201657x BindingDB Entry DOI: 10.7270/Q29024V1
					More data for this Ligand-Target Pair