BDBM50387180 CHEMBL2047998
SMILES: CCOC(=O)Cn1c2ccc(O)cc2s\c1=N\C(N)=N
InChI Key: InChIKey=QHEKEKSMRXTAKP-NTCAYCPXSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Trypsin (Homo sapiens (Human)) | BDBM50387180 (CHEMBL2047998) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.68E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometry | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-1 (Homo sapiens (Human)) | BDBM50387180 (CHEMBL2047998) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.98E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin 1 using tosyl-GPR-pNA substrate by spectrophotometry | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50387180 (CHEMBL2047998) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.81E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human thrombin using tosyl-GPR-pNA substrate by spectrophotometry | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50387180 (CHEMBL2047998) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 9.50E+4 | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Binding affinity to human alpha thrombin by Biocore A100 assay | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair |