BDBM50387347 CHEMBL2046641

SMILES: Nc1ncccc1C(=O)c1cccc(n1)N1CCN[C@@H](C1)c1ccccc1

InChI Key: InChIKey=ZYTHRQIDZFTPKA-SFHVURJKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387347 (CHEMBL2046641) Show SMILES Nc1ncccc1C(=O)c1cccc(n1)N1CCN[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C21H21N5O/c22-21-16(8-5-11-24-21)20(27)17-9-4-10-19(25-17)26-13-12-23-18(14-26)15-6-2-1-3-7-15/h1-11,18,23H,12-14H2,(H2,22,24)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	238	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair