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BDBM50387482 CHEMBL2047480

SMILES: CC1(C)\C(=C\C=C/C2=[N+](CCCc3ccccc3)c3ccccc3C2(C)C)N(CCCc2ccccc2)c2ccccc12

InChI Key: InChIKey=JZRARWAVGWQOTL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387482   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-arginine N-methyltransferase 1


(Homo sapiens (Human))		BDBM50387482
PNG
(CHEMBL2047480)
Show SMILES CC1(C)\C(=C\C=C/C2=[N+](CCCc3ccccc3)c3ccccc3C2(C)C)N(CCCc2ccccc2)c2ccccc12 |c:7|
Show InChI InChI=1S/C41H45N2/c1-40(2)34-24-11-13-26-36(34)42(30-16-22-32-18-7-5-8-19-32)38(40)28-15-29-39-41(3,4)35-25-12-14-27-37(35)43(39)31-17-23-33-20-9-6-10-21-33/h5-15,18-21,24-29H,16-17,22-23,30-31H2,1-4H3/q+1
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Article
PubMed
n/an/a 6.30E+3n/an/an/an/an/an/a



Georgia State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins ...

Eur J Med Chem 54: 647-59 (2012)


Article DOI: 10.1016/j.ejmech.2012.06.017
BindingDB Entry DOI: 10.7270/Q2XD12R6
More data for this
Ligand-Target Pair