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BDBM50387484 CHEMBL2047482

SMILES: CC1(C)\C(=C\C=C/C2=[N+](CCC[N+](C)(C)C)c3ccc(Br)cc3C2(C)C)N(CCC[N+](C)(C)C)c2ccc(Br)cc12

InChI Key: InChIKey=TXXWZCUWVCEGME-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387484   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-arginine N-methyltransferase 1


(Homo sapiens (Human))		BDBM50387484
PNG
(CHEMBL2047482)
Show SMILES CC1(C)\C(=C\C=C/C2=[N+](CCC[N+](C)(C)C)c3ccc(Br)cc3C2(C)C)N(CCC[N+](C)(C)C)c2ccc(Br)cc12 |c:7|
Show InChI InChI=1S/C35H51Br2N4/c1-34(2)28-24-26(36)16-18-30(28)38(20-12-22-40(5,6)7)32(34)14-11-15-33-35(3,4)29-25-27(37)17-19-31(29)39(33)21-13-23-41(8,9)10/h11,14-19,24-25H,12-13,20-23H2,1-10H3/q+3
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Similars
Article
PubMed
n/an/a 2.92E+5n/an/an/an/an/an/a



Georgia State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins ...

Eur J Med Chem 54: 647-59 (2012)


Article DOI: 10.1016/j.ejmech.2012.06.017
BindingDB Entry DOI: 10.7270/Q2XD12R6
More data for this
Ligand-Target Pair