BDBM50387604 CHEMBL2058599

SMILES: CCC(C1CC1)n1c2nccc(-c3cc(Cl)c(OC)cc3OC)c2nc(C)c1=O

InChI Key: InChIKey=RHURQGMRFGKHMD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor (Rattus norvegicus (rat))	BDBM50387604 (CHEMBL2058599) Show SMILES CCC(C1CC1)n1c2nccc(-c3cc(Cl)c(OC)cc3OC)c2nc(C)c1=O Show InChI InChI=1S/C22H24ClN3O3/c1-5-17(13-6-7-13)26-21-20(25-12(2)22(26)27)14(8-9-24-21)15-10-16(23)19(29-4)11-18(15)28-3/h8-11,13,17H,5-7H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Antagonist activity at rat CFR1R				Bioorg Med Chem Lett 22: 4986-9 (2012) Article DOI: 10.1016/j.bmcl.2012.06.034 BindingDB Entry DOI: 10.7270/Q23X87Q6
					More data for this Ligand-Target Pair