BDBM50387624 CHEMBL2058327

SMILES: CCCC(C1CC1)n1c2nccc(-c3ccc(Cl)cc3Cl)c2nc(C)c1=O

InChI Key: InChIKey=NLZBSIOTBMXFKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387624   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor (Rattus norvegicus (rat))	BDBM50387624 (CHEMBL2058327) Show SMILES CCCC(C1CC1)n1c2nccc(-c3ccc(Cl)cc3Cl)c2nc(C)c1=O Show InChI InChI=1S/C21H21Cl2N3O/c1-3-4-18(13-5-6-13)26-20-19(25-12(2)21(26)27)16(9-10-24-20)15-8-7-14(22)11-17(15)23/h7-11,13,18H,3-6H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Antagonist activity at rat CFR1R				Bioorg Med Chem Lett 22: 4986-9 (2012) Article DOI: 10.1016/j.bmcl.2012.06.034 BindingDB Entry DOI: 10.7270/Q23X87Q6
					More data for this Ligand-Target Pair