BDBM50387636 CHEMBL2058589

SMILES: CCOc1cc(Cl)c(cc1C)-c1ccnc2n(C(CC)C3CC3)c(=O)c(C)nc12

InChI Key: InChIKey=DSFJJLJFMCMDCW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor (Rattus norvegicus (rat))	BDBM50387636 (CHEMBL2058589) Show SMILES CCOc1cc(Cl)c(cc1C)-c1ccnc2n(C(CC)C3CC3)c(=O)c(C)nc12 Show InChI InChI=1S/C23H26ClN3O2/c1-5-19(15-7-8-15)27-22-21(26-14(4)23(27)28)16(9-10-25-22)17-11-13(3)20(29-6-2)12-18(17)24/h9-12,15,19H,5-8H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co Curated by ChEMBL					Assay Description Antagonist activity at rat CFR1R				Bioorg Med Chem Lett 22: 4986-9 (2012) Article DOI: 10.1016/j.bmcl.2012.06.034 BindingDB Entry DOI: 10.7270/Q23X87Q6
					More data for this Ligand-Target Pair