BDBM50387768 CHEMBL2057507

SMILES: Clc1ccc(cn1)S(=O)(=O)N1CC(C1)C(=O)N1CCN(CC1)c1ccncc1

InChI Key: InChIKey=AZXRZTIOMCILRA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387768 (CHEMBL2057507) Show SMILES Clc1ccc(cn1)S(=O)(=O)N1CC(C1)C(=O)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C18H20ClN5O3S/c19-17-2-1-16(11-21-17)28(26,27)24-12-14(13-24)18(25)23-9-7-22(8-10-23)15-3-5-20-6-4-15/h1-6,11,14H,7-10,12-13H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387768 (CHEMBL2057507) Show SMILES Clc1ccc(cn1)S(=O)(=O)N1CC(C1)C(=O)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C18H20ClN5O3S/c19-17-2-1-16(11-21-17)28(26,27)24-12-14(13-24)18(25)23-9-7-22(8-10-23)15-3-5-20-6-4-15/h1-6,11,14H,7-10,12-13H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair