BDBM50388533 CHEMBL2058838

SMILES: Cc1ccc(Nc2c(nc3n2CCN(C(=O)C(C)(C)N)C3(C)C)-c2ccc(F)cc2)cc1

InChI Key: InChIKey=QIZBBXZGNNKGNT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50388533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50388533 (CHEMBL2058838) Show SMILES Cc1ccc(Nc2c(nc3n2CCN(C(=O)C(C)(C)N)C3(C)C)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H30FN5O/c1-16-6-12-19(13-7-16)28-21-20(17-8-10-18(26)11-9-17)29-22-25(4,5)31(15-14-30(21)22)23(32)24(2,3)27/h6-13,28H,14-15,27H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human ERG channel expressed in CHO cells by patch clamp assay				J Med Chem 55: 4244-73 (2012) Article DOI: 10.1021/jm300041e BindingDB Entry DOI: 10.7270/Q21V5G1P
					More data for this Ligand-Target Pair