BDBM50388830 CHEMBL2062756
SMILES: OC(=O)CN1C(=S)S\C(=C/c2csc3ccc(Cl)cc23)C1=O
InChI Key: InChIKey=MLUFAPWPCYDSJX-JYOAFUTRSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dynamin-1 (Homo sapiens (Human)) | BDBM50388830 (CHEMBL2062756) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re... | ACS Med Chem Lett 3: 352-356 (2012) Article DOI: 10.1021/ml200284s BindingDB Entry DOI: 10.7270/Q2V40W83 | |||||||||||
More data for this Ligand-Target Pair |