BDBM50388874 CHEMBL1967720
SMILES: CC(C)(C(N)=O)n1cc(cn1)-c1cnc(N)c2c(csc12)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1
InChI Key: InChIKey=BIKYDWLMTPRSQL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50388874 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Macrophage colony stimulating factor receptor
(Homo sapiens (Human)) | BDBM50388874
(CHEMBL1967720)Show SMILES CC(C)(C(N)=O)n1cc(cn1)-c1cnc(N)c2c(csc12)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 Show InChI InChI=1S/C27H24FN7O2S/c1-27(2,25(30)36)35-13-16(11-32-35)20-12-31-24(29)22-21(14-38-23(20)22)15-6-8-18(9-7-15)33-26(37)34-19-5-3-4-17(28)10-19/h3-14H,1-2H3,(H2,29,31)(H2,30,36)(H2,33,34,37) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R |
ACS Med Chem Lett 3: 383-386 (2012)
Article DOI: 10.1021/ml300012r
BindingDB Entry DOI: 10.7270/Q2B56KTH |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50388874
(CHEMBL1967720)Show SMILES CC(C)(C(N)=O)n1cc(cn1)-c1cnc(N)c2c(csc12)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 Show InChI InChI=1S/C27H24FN7O2S/c1-27(2,25(30)36)35-13-16(11-32-35)20-12-31-24(29)22-21(14-38-23(20)22)15-6-8-18(9-7-15)33-26(37)34-19-5-3-4-17(28)10-19/h3-14H,1-2H3,(H2,29,31)(H2,30,36)(H2,33,34,37) | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRA |
ACS Med Chem Lett 3: 383-386 (2012)
Article DOI: 10.1021/ml300012r
BindingDB Entry DOI: 10.7270/Q2B56KTH |
More data for this
Ligand-Target Pair | |
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