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BDBM50388886 CHEMBL2063122

SMILES: CC(=O)NC1CCCOc2c1nn(c2-c1ccc(Cl)cc1)-c1ccccc1Cl

InChI Key: InChIKey=DZFJCOBMNWBMOF-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388886   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50388886
PNG
(CHEMBL2063122)
Show SMILES CC(=O)NC1CCCOc2c1nn(c2-c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C21H19Cl2N3O2/c1-13(27)24-17-6-4-12-28-21-19(17)25-26(18-7-3-2-5-16(18)23)20(21)14-8-10-15(22)11-9-14/h2-3,5,7-11,17H,4,6,12H2,1H3,(H,24,27)
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PC cid
PC sid
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Article
PubMed
0.75n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]SR141716A form human CB1 receptor expressed in HEK293 cells after 60 mins by beta counting


ACS Med Chem Lett 3: 397-401 (2012)


Article DOI: 10.1021/ml3000325
BindingDB Entry DOI: 10.7270/Q22N53BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50388886
PNG
(CHEMBL2063122)
Show SMILES CC(=O)NC1CCCOc2c1nn(c2-c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C21H19Cl2N3O2/c1-13(27)24-17-6-4-12-28-21-19(17)25-26(18-7-3-2-5-16(18)23)20(21)14-8-10-15(22)11-9-14/h2-3,5,7-11,17H,4,6,12H2,1H3,(H,24,27)
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Article
PubMed
0.870n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP-55940-induced [35S]GTPgammaS binding incubated for 1...


ACS Med Chem Lett 3: 397-401 (2012)


Article DOI: 10.1021/ml3000325
BindingDB Entry DOI: 10.7270/Q22N53BD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50388886
PNG
(CHEMBL2063122)
Show SMILES CC(=O)NC1CCCOc2c1nn(c2-c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C21H19Cl2N3O2/c1-13(27)24-17-6-4-12-28-21-19(17)25-26(18-7-3-2-5-16(18)23)20(21)14-8-10-15(22)11-9-14/h2-3,5,7-11,17H,4,6,12H2,1H3,(H,24,27)
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UniChem
Article
PubMed
2.06E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO-K1 cells after 60 mins by beta counting


ACS Med Chem Lett 3: 397-401 (2012)


Article DOI: 10.1021/ml3000325
BindingDB Entry DOI: 10.7270/Q22N53BD
More data for this
Ligand-Target Pair