BDBM50389284 CHEMBL2063758
SMILES: CCNC(=O)Nc1ccc(cc1)-c1nc2CCS(=O)(=O)c2c(n1)N1CCOC[C@H]1C
InChI Key: InChIKey=BVSJXRHPGPVNHX-CYBMUJFWSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase mTOR (Homo sapiens (Human)) | BDBM50389284 (CHEMBL2063758) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of mTOR | Bioorg Med Chem Lett 22: 5114-7 (2012) Article DOI: 10.1016/j.bmcl.2012.05.104 BindingDB Entry DOI: 10.7270/Q29024WG | |||||||||||
More data for this Ligand-Target Pair |