BDBM50389348 CHEMBL2064097

SMILES: COc1ccc(Cn2cc([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c3c(F)cccc23)cc1

InChI Key: InChIKey=LCXPEPAEMKBEOC-PMXSJFBMSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50389348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50389348 (CHEMBL2064097) Show SMILES COc1ccc(Cn2cc([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c3c(F)cccc23)cc1 |r| Show InChI InChI=1S/C21H22FNO5/c1-27-13-7-5-12(6-8-13)9-23-10-14(18-15(22)3-2-4-16(18)23)21-20(26)19(25)17(24)11-28-21/h2-8,10,17,19-21,24-26H,9,11H2,1H3/t17-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.43E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assay				Eur J Med Chem 55: 32-8 (2012) Article DOI: 10.1016/j.ejmech.2012.06.053 BindingDB Entry DOI: 10.7270/Q2S183K0
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50389348 (CHEMBL2064097) Show SMILES COc1ccc(Cn2cc([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c3c(F)cccc23)cc1 |r| Show InChI InChI=1S/C21H22FNO5/c1-27-13-7-5-12(6-8-13)9-23-10-14(18-15(22)3-2-4-16(18)23)21-20(26)19(25)17(24)11-28-21/h2-8,10,17,19-21,24-26H,9,11H2,1H3/t17-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells incubated for 120 mins at 37 degC by [14C]-AMG uptake assay				Eur J Med Chem 55: 32-8 (2012) Article DOI: 10.1016/j.ejmech.2012.06.053 BindingDB Entry DOI: 10.7270/Q2S183K0
					More data for this Ligand-Target Pair