BDBM50389932 CHEMBL2071068

SMILES: CC(O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1

InChI Key: InChIKey=AFRWXKHLYPWETA-UHFFFAOYSA-N

Data: 1 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50389932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50389932 (CHEMBL2071068) Show SMILES CC(O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H28ClN3O2/c1-16(29)22-20-15-18(25)7-10-21(20)27-23(22)24(30)26-12-11-17-5-8-19(9-6-17)28-13-3-2-4-14-28/h5-10,15-16,27,29H,2-4,11-14H2,1H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 5 mins ...				J Med Chem 58: 5979-88 (2015) Article DOI: 10.1021/acs.jmedchem.5b00579 BindingDB Entry DOI: 10.7270/Q2PG1TG7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50389932 (CHEMBL2071068) Show SMILES CC(O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H28ClN3O2/c1-16(29)22-20-15-18(25)7-10-21(20)27-23(22)24(30)26-12-11-17-5-8-19(9-6-17)28-13-3-2-4-14-28/h5-10,15-16,27,29H,2-4,11-14H2,1H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.97E+3	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 5 mins ...				J Med Chem 58: 5979-88 (2015) Article DOI: 10.1021/acs.jmedchem.5b00579 BindingDB Entry DOI: 10.7270/Q2PG1TG7
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50389932 (CHEMBL2071068) Show SMILES CC(O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H28ClN3O2/c1-16(29)22-20-15-18(25)7-10-21(20)27-23(22)24(30)26-12-11-17-5-8-19(9-6-17)28-13-3-2-4-14-28/h5-10,15-16,27,29H,2-4,11-14H2,1H3,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Allosteric modulation of human recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of [3H]CP55940 binding				J Med Chem 55: 5627-31 (2012) Article DOI: 10.1021/jm201485c BindingDB Entry DOI: 10.7270/Q27W6D8K
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50389932 (CHEMBL2071068) Show SMILES CC(O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H28ClN3O2/c1-16(29)22-20-15-18(25)7-10-21(20)27-23(22)24(30)26-12-11-17-5-8-19(9-6-17)28-13-3-2-4-14-28/h5-10,15-16,27,29H,2-4,11-14H2,1H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.66E+3	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 15 mins...				J Med Chem 58: 5979-88 (2015) Article DOI: 10.1021/acs.jmedchem.5b00579 BindingDB Entry DOI: 10.7270/Q2PG1TG7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50389932 (CHEMBL2071068) Show SMILES CC(O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H28ClN3O2/c1-16(29)22-20-15-18(25)7-10-21(20)27-23(22)24(30)26-12-11-17-5-8-19(9-6-17)28-13-3-2-4-14-28/h5-10,15-16,27,29H,2-4,11-14H2,1H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.45E+3	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Allosteric modulation of human recombinant CB1 receptor expressed in HEK293 cells assessed as stimulation of [3H]CP55940 binding				J Med Chem 55: 5627-31 (2012) Article DOI: 10.1021/jm201485c BindingDB Entry DOI: 10.7270/Q27W6D8K
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50389932 (CHEMBL2071068) Show SMILES CC(O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C24H28ClN3O2/c1-16(29)22-20-15-18(25)7-10-21(20)27-23(22)24(30)26-12-11-17-5-8-19(9-6-17)28-13-3-2-4-14-28/h5-10,15-16,27,29H,2-4,11-14H2,1H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 10 mins...				J Med Chem 58: 5979-88 (2015) Article DOI: 10.1021/acs.jmedchem.5b00579 BindingDB Entry DOI: 10.7270/Q2PG1TG7
					More data for this Ligand-Target Pair