Found 2 hits for monomerid = 50389979 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50389979
(CHEMBL2071207)Show SMILES Cn1cc(Nc2ncc(c(N[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3C(=O)NC3CC3)n2)C(F)(F)F)cn1 |r,c:15| Show InChI InChI=1S/C20H22F3N7O/c1-30-9-13(7-25-30)27-19-24-8-14(20(21,22)23)17(29-19)28-16-11-3-2-10(6-11)15(16)18(31)26-12-4-5-12/h2-3,7-12,15-16H,4-6H2,1H3,(H,26,31)(H2,24,27,28,29)/t10-,11+,15+,16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 292 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of KDR by HTRF analysis in presence of 1 mM ATP |
Bioorg Med Chem Lett 22: 4750-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.067 BindingDB Entry DOI: 10.7270/Q20C4WTF |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50389979
(CHEMBL2071207)Show SMILES Cn1cc(Nc2ncc(c(N[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3C(=O)NC3CC3)n2)C(F)(F)F)cn1 |r,c:15| Show InChI InChI=1S/C20H22F3N7O/c1-30-9-13(7-25-30)27-19-24-8-14(20(21,22)23)17(29-19)28-16-11-3-2-10(6-11)15(16)18(31)26-12-4-5-12/h2-3,7-12,15-16H,4-6H2,1H3,(H,26,31)(H2,24,27,28,29)/t10-,11+,15+,16-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of Aurora B kinase by HTRF analysis in presence of 1 mM ATP |
Bioorg Med Chem Lett 22: 4750-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.067 BindingDB Entry DOI: 10.7270/Q20C4WTF |
More data for this Ligand-Target Pair | |