Found 2 hits for monomerid = 50389980 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50389980
(CHEMBL2071208)Show SMILES Cn1cc(Nc2ncc(c(N[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3C(=O)NCCO)n2)C(F)(F)F)cn1 |r,c:15| Show InChI InChI=1S/C19H22F3N7O2/c1-29-9-12(7-25-29)26-18-24-8-13(19(20,21)22)16(28-18)27-15-11-3-2-10(6-11)14(15)17(31)23-4-5-30/h2-3,7-11,14-15,30H,4-6H2,1H3,(H,23,31)(H2,24,26,27,28)/t10-,11+,14+,15-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 266 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of KDR by HTRF analysis in presence of 1 mM ATP |
Bioorg Med Chem Lett 22: 4750-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.067
BindingDB Entry DOI: 10.7270/Q20C4WTF |
More data for this
Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50389980
(CHEMBL2071208)Show SMILES Cn1cc(Nc2ncc(c(N[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3C(=O)NCCO)n2)C(F)(F)F)cn1 |r,c:15| Show InChI InChI=1S/C19H22F3N7O2/c1-29-9-12(7-25-29)26-18-24-8-13(19(20,21)22)16(28-18)27-15-11-3-2-10(6-11)14(15)17(31)23-4-5-30/h2-3,7-11,14-15,30H,4-6H2,1H3,(H,23,31)(H2,24,26,27,28)/t10-,11+,14+,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Aurora B kinase by HTRF analysis in presence of 1 mM ATP |
Bioorg Med Chem Lett 22: 4750-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.067
BindingDB Entry DOI: 10.7270/Q20C4WTF |
More data for this
Ligand-Target Pair | |
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