BDBM50390367 CHEMBL2070907

SMILES: Cc1nc(cs1)-c1nc(N)c2nnn(CC3CCCCO3)c2n1

InChI Key: InChIKey=QXXVYDZDDGYKQA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 8 (Homo sapiens (Human))	BDBM50390367 (CHEMBL2070907) Show SMILES Cc1nc(cs1)-c1nc(N)c2nnn(CC3CCCCO3)c2n1 Show InChI InChI=1S/C14H17N7OS/c1-8-16-10(7-23-8)13-17-12(15)11-14(18-13)21(20-19-11)6-9-4-2-3-5-22-9/h7,9H,2-6H2,1H3,(H2,15,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE8B expressed in Sf9 insect cells				Bioorg Med Chem Lett 22: 5721-6 (2012) Article DOI: 10.1016/j.bmcl.2012.06.079 BindingDB Entry DOI: 10.7270/Q2J67J0X
					More data for this Ligand-Target Pair