BDBM50390455 CHEMBL2071449

SMILES: CC(NC(=O)c1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=UAAGAPAGCIEIPW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50390455 (CHEMBL2071449) Show SMILES CC(NC(=O)c1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C22H23Cl2FN6O/c1-12(19-17(23)2-3-18(25)20(19)24)30-22(32)16-8-13(9-28-21(16)26)14-10-29-31(11-14)15-4-6-27-7-5-15/h2-3,8-12,15,27H,4-7H2,1H3,(H2,26,28)(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met incubated for 60 mins at spectrophotometry				Bioorg Med Chem 20: 5169-80 (2012) Article DOI: 10.1016/j.bmc.2012.07.007 BindingDB Entry DOI: 10.7270/Q2WH2R32
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50390455 (CHEMBL2071449) Show SMILES CC(NC(=O)c1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C22H23Cl2FN6O/c1-12(19-17(23)2-3-18(25)20(19)24)30-22(32)16-8-13(9-28-21(16)26)14-10-29-31(11-14)15-4-6-27-7-5-15/h2-3,8-12,15,27H,4-7H2,1H3,(H2,26,28)(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				Bioorg Med Chem 21: 6804-20 (2013) Article DOI: 10.1016/j.bmc.2013.07.032 BindingDB Entry DOI: 10.7270/Q27P90TV
					More data for this Ligand-Target Pair