BDBM50390502 CHEMBL2071616

SMILES: Cc1cc(ccc1Nc1nc2ccc(cc2[nH]1)C#N)C(C)(C)C

InChI Key: InChIKey=JVJMBEIMKJSYGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50390502 (CHEMBL2071616) Show SMILES Cc1cc(ccc1Nc1nc2ccc(cc2[nH]1)C#N)C(C)(C)C Show InChI InChI=1S/C19H20N4/c1-12-9-14(19(2,3)4)6-8-15(12)21-18-22-16-7-5-13(11-20)10-17(16)23-18/h5-10H,1-4H3,(H2,21,22,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CK1delta by Lance assay				Bioorg Med Chem Lett 22: 5392-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.046 BindingDB Entry DOI: 10.7270/Q2CF9R6Q
					More data for this Ligand-Target Pair