BDBM50390507 CHEMBL2071625

SMILES: CC(C)(C)c1ccc(Nc2cn3cc(ccc3n2)C#N)cc1

InChI Key: InChIKey=OAKZCBWDPYHGBN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I (Homo sapiens (Human))	BDBM50390507 (CHEMBL2071625) Show SMILES CC(C)(C)c1ccc(Nc2cn3cc(ccc3n2)C#N)cc1 Show InChI InChI=1S/C18H18N4/c1-18(2,3)14-5-7-15(8-6-14)20-16-12-22-11-13(10-19)4-9-17(22)21-16/h4-9,11-12,20H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblotting				Bioorg Med Chem Lett 22: 5392-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.046 BindingDB Entry DOI: 10.7270/Q2CF9R6Q
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50390507 (CHEMBL2071625) Show SMILES CC(C)(C)c1ccc(Nc2cn3cc(ccc3n2)C#N)cc1 Show InChI InChI=1S/C18H18N4/c1-18(2,3)14-5-7-15(8-6-14)20-16-12-22-11-13(10-19)4-9-17(22)21-16/h4-9,11-12,20H,1-3H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CK1delta by Lance assay				Bioorg Med Chem Lett 22: 5392-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.046 BindingDB Entry DOI: 10.7270/Q2CF9R6Q
					More data for this Ligand-Target Pair