Found 3 hits for monomerid = 50390664 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aldo-keto reductase family 1 member C1
(Homo sapiens (Human)) | BDBM50390664
(CHEMBL2070008)Show SMILES CCCCOc1cc(ccc1[N+]([O-])=O)C(=O)Nc1ccccc1C(O)=O Show InChI InChI=1S/C18H18N2O6/c1-2-3-10-26-16-11-12(8-9-15(16)20(24)25)17(21)19-14-7-5-4-6-13(14)18(22)23/h4-9,11H,2-3,10H2,1H3,(H,19,21)(H,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description Inhibition of recombinant AKR1C1 using 1-acenaphthenol as substrate by spectrophotometry |
Bioorg Med Chem Lett 22: 5948-51 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.062 BindingDB Entry DOI: 10.7270/Q2BK1DFR |
More data for this Ligand-Target Pair | |
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3)
(Homo sapiens (Human)) | BDBM50390664
(CHEMBL2070008)Show SMILES CCCCOc1cc(ccc1[N+]([O-])=O)C(=O)Nc1ccccc1C(O)=O Show InChI InChI=1S/C18H18N2O6/c1-2-3-10-26-16-11-12(8-9-15(16)20(24)25)17(21)19-14-7-5-4-6-13(14)18(22)23/h4-9,11H,2-3,10H2,1H3,(H,19,21)(H,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description Inhibition of recombinant AKR1C3 using 1-acenaphthenol as substrate by spectrophotometry |
Bioorg Med Chem Lett 22: 5948-51 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.062 BindingDB Entry DOI: 10.7270/Q2BK1DFR |
More data for this Ligand-Target Pair | |
Aldo-keto reductase family 1 member C2
(Homo sapiens (Human)) | BDBM50390664
(CHEMBL2070008)Show SMILES CCCCOc1cc(ccc1[N+]([O-])=O)C(=O)Nc1ccccc1C(O)=O Show InChI InChI=1S/C18H18N2O6/c1-2-3-10-26-16-11-12(8-9-15(16)20(24)25)17(21)19-14-7-5-4-6-13(14)18(22)23/h4-9,11H,2-3,10H2,1H3,(H,19,21)(H,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana
Curated by ChEMBL
| Assay Description Inhibition of recombinant AKR1C2 using 1-acenaphthenol as substrate by spectrophotometry |
Bioorg Med Chem Lett 22: 5948-51 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.062 BindingDB Entry DOI: 10.7270/Q2BK1DFR |
More data for this Ligand-Target Pair | |