Found 8 hits for monomerid = 50390681 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase
(Homo sapiens (Human)) | BDBM50390681
(CHEMBL2070207)Show InChI InChI=1S/C14H13N3O2/c1-2-17-8-10(9-5-3-4-6-13(9)17)11-7-12(14(18)19)16-15-11/h3-8H,2H2,1H3,(H,15,16)(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sassari
Curated by ChEMBL
| Assay Description Inhibition of recombinant human full-length carbonic anhydrase 1 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-... |
ACS Med Chem Lett 8: 941-946 (2017)
Article DOI: 10.1021/acsmedchemlett.7b00229 BindingDB Entry DOI: 10.7270/Q2ZK5K8P |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50390681
(CHEMBL2070207)Show InChI InChI=1S/C14H13N3O2/c1-2-17-8-10(9-5-3-4-6-13(9)17)11-7-12(14(18)19)16-15-11/h3-8H,2H2,1H3,(H,15,16)(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Inhibition of human CA1 using CO2 as substrate incubated for 6 hrs prior to substrate addition measured for 10 to 100 secs by stopped flow technique |
Bioorg Med Chem Lett 22: 5801-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.094 BindingDB Entry DOI: 10.7270/Q2319X0G |
More data for this Ligand-Target Pair | |
Carbonic anhydrase
(Homo sapiens (Human)) | BDBM50390681
(CHEMBL2070207)Show InChI InChI=1S/C14H13N3O2/c1-2-17-8-10(9-5-3-4-6-13(9)17)11-7-12(14(18)19)16-15-11/h3-8H,2H2,1H3,(H,15,16)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sassari
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase 12 catalytic domain preincubated for 15 mins prior to testing measured for 10 to 100 secs by pheno... |
ACS Med Chem Lett 8: 941-946 (2017)
Article DOI: 10.1021/acsmedchemlett.7b00229 BindingDB Entry DOI: 10.7270/Q2ZK5K8P |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50390681
(CHEMBL2070207)Show InChI InChI=1S/C14H13N3O2/c1-2-17-8-10(9-5-3-4-6-13(9)17)11-7-12(14(18)19)16-15-11/h3-8H,2H2,1H3,(H,15,16)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Inhibition of human CA12 using CO2 as substrate incubated for 6 hrs prior to substrate addition measured for 10 to 100 secs by stopped flow technique |
Bioorg Med Chem Lett 22: 5801-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.094 BindingDB Entry DOI: 10.7270/Q2319X0G |
More data for this Ligand-Target Pair | |
Carbonic anhydrases; II & IX
(Homo sapiens (Human)) | BDBM50390681
(CHEMBL2070207)Show InChI InChI=1S/C14H13N3O2/c1-2-17-8-10(9-5-3-4-6-13(9)17)11-7-12(14(18)19)16-15-11/h3-8H,2H2,1H3,(H,15,16)(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sassari
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase 9 catalytic domain preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol... |
ACS Med Chem Lett 8: 941-946 (2017)
Article DOI: 10.1021/acsmedchemlett.7b00229 BindingDB Entry DOI: 10.7270/Q2ZK5K8P |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50390681
(CHEMBL2070207)Show InChI InChI=1S/C14H13N3O2/c1-2-17-8-10(9-5-3-4-6-13(9)17)11-7-12(14(18)19)16-15-11/h3-8H,2H2,1H3,(H,15,16)(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Inhibition of human CA9 using CO2 as substrate incubated for 6 hrs prior to substrate addition measured for 10 to 100 secs by stopped flow technique |
Bioorg Med Chem Lett 22: 5801-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.094 BindingDB Entry DOI: 10.7270/Q2319X0G |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50390681
(CHEMBL2070207)Show InChI InChI=1S/C14H13N3O2/c1-2-17-8-10(9-5-3-4-6-13(9)17)11-7-12(14(18)19)16-15-11/h3-8H,2H2,1H3,(H,15,16)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.82E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Sassari
Curated by ChEMBL
| Assay Description Inhibition of human CA2 using CO2 as substrate incubated for 6 hrs prior to substrate addition measured for 10 to 100 secs by stopped flow technique |
Bioorg Med Chem Lett 22: 5801-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.094 BindingDB Entry DOI: 10.7270/Q2319X0G |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50390681
(CHEMBL2070207)Show InChI InChI=1S/C14H13N3O2/c1-2-17-8-10(9-5-3-4-6-13(9)17)11-7-12(14(18)19)16-15-11/h3-8H,2H2,1H3,(H,15,16)(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.82E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sassari
Curated by ChEMBL
| Assay Description Inhibition of recombinant human full-length carbonic anhydrase 2 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-... |
ACS Med Chem Lett 8: 941-946 (2017)
Article DOI: 10.1021/acsmedchemlett.7b00229 BindingDB Entry DOI: 10.7270/Q2ZK5K8P |
More data for this Ligand-Target Pair | |