BDBM50390898 CHEMBL2070992

SMILES: COc1ccc(cc1)-c1csc(NC(=O)CCNS(=O)(=O)c2ccc(C)cc2)n1

InChI Key: InChIKey=LXALJDUZPWJNTP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50390898 (CHEMBL2070992) Show SMILES COc1ccc(cc1)-c1csc(NC(=O)CCNS(=O)(=O)c2ccc(C)cc2)n1 Show InChI InChI=1S/C20H21N3O4S2/c1-14-3-9-17(10-4-14)29(25,26)21-12-11-19(24)23-20-22-18(13-28-20)15-5-7-16(27-2)8-6-15/h3-10,13,21H,11-12H2,1-2H3,(H,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay				Bioorg Med Chem Lett 22: 5936-41 (2012) Article DOI: 10.1016/j.bmcl.2012.07.060 BindingDB Entry DOI: 10.7270/Q25T3MKN
					More data for this Ligand-Target Pair